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(a) Explain sensitivity and selectivity in terms of true and false positives.

(b) What is the advantage of a Needleman-Wunsch alignment compared to a seeded alignment?

(c) What does the expectation parameter mean in local alignment? What will happen if the expectation value is increased from its default value of 10 to a 100?


Two proteins have 20 % sequence identity. Is this likely to be significant? What other simple piece of information do you need to answer this question properly?


The ability of hemoglobin (Hb) to carry oxygen throughout the body as oxyhemoglobin (HbO2) is dependent on the pH of the blood. What effect would acidosis have on the ability of a patient to transport oxygen?


Why is the PI of human insulin higher than PI of duck insulin


How many grams of aluminum oxide are produced from the synthesis reaction of 8.7 g of Al with oxygen gas? 4Al + 3O2 -> 2Al2O3


Aerobic breakdown of sugar yields 2870 kJ of energy per mole, whereas anaerobic breakdown of sugar yields no more than 210 kJ per mole. Explain this drastic difference in energy in terms of the processes that occur in aerobic vs. anaerobic processes.  *

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_&_ is a characteristic chewing organ of sea urchins


During the bypass surgery for coronary heart disease patient, can the surgeon remove the semi-lunar valves of the vein taken from the leg or it must be inserted with the semi-lunar valves with care to prevent that valves become against the blood flow direction


If the sequence of bases in DNA TAGC then the sequence of bases in RNA will be : *




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