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In humans there is a disease called Phenylketonuria (PKU) which is caused by a recessive allele. People with this allele have a defective enzyme and cannot break down the amino acid phenylalanine. This disease can result in mental disability or death. Let "E" represent the normal enzyme. Also in humans is a condition called galactose intolerance or galactosemia, which is also caused by a recessive allele. Let "G" represent the normal allele for galactose digestion. In both diseases, normal dominates over recessive. If two adults were heterozygous for both traits (EeGg), what are the chances of having a child that is completely normal? Has just PKU? Has just galactosemia? Has both diseases?
Biology
Which of the following statements best describes pharmacokinetics?
1. The study of how drugs reach their target in the body and how the levels of a drug
in the blood are affected by various factors.
2. The study of how drugs can be designed using molecular modelling based on a
drug's pharmacophore.
3. The study of how a drug interacts with its target binding site at the molecular level.
4. The study of which functional groups are important in binding a drug to its target
binding site and the identification of a pharmacophore.
1. The study of how drugs reach their target in the body and how the levels of a drug
in the blood are affected by various factors.
2. The study of how drugs can be designed using molecular modelling based on a
drug's pharmacophore.
3. The study of how a drug interacts with its target binding site at the molecular level.
4. The study of which functional groups are important in binding a drug to its target
binding site and the identification of a pharmacophore.
Biology
Sometimes drug metabolism processes become more effective, which can lead to:
1. Drug toxicity
2. Drug tolerance
3. Drug overdose
4. Liver failure
1. Drug toxicity
2. Drug tolerance
3. Drug overdose
4. Liver failure
Biology
The distribution of drugs into the central nervous system (brain) usually depends on?
1. Aqueous diffusion
2. Lipid diffusion
3. Active transport
4. Facilitated transport
5. Receptor-mediated endocytosis
1. Aqueous diffusion
2. Lipid diffusion
3. Active transport
4. Facilitated transport
5. Receptor-mediated endocytosis
Biology
What are the protein structures called that are expressed within the cell membranes and
interact with endogenous signalling molecules or some drugs to initiate an intracellular
response?
1. Enzymes
2. Hormones
3. Ligands
4. Receptors
interact with endogenous signalling molecules or some drugs to initiate an intracellular
response?
1. Enzymes
2. Hormones
3. Ligands
4. Receptors
Biology
Which of the following is NOT a type of cellular receptor?
1. Tyrosine kinase receptor
2. G-protein coupled receptor
3. Endocrine receptors
4. Intracellular/nuclear receptor.
1. Tyrosine kinase receptor
2. G-protein coupled receptor
3. Endocrine receptors
4. Intracellular/nuclear receptor.
Describe the different mechanisms of action of antibacterial agents.
Discuss the common mechanisms by which drug resistance occur.
What are antibiotic resistance strains?
Briefly describe Two techniques ideal for identification of viral pathogens
