A 45 year-old woman complaining of breast pain was diagnosed with having HER2-positive breast cancer. The patient underwent lumpectomy followed by a period of chemotherapy including adjuvant treatment. Over the course of their treatment, the patient developed a urinary tract infection that required antimicrobial therapy, which initially consisted of atrimethoprim / sulfametoxazole combination drug. However, the patient during the course of her therapy suffered multiple recurrent infections and was, consequently, enrolled in a clinical trial to test the efficacy of a new mannoside anti-infective agent. Question: With reference to signaling pathways, discuss the pathogenesis of HER2-positive breast cancer. In your answer, include discussion on the differential diagnosis of this condition.
What gives shape to bacteria cell
What is the difference in the function of the glycoprotein structures of an HIV virion and the cilia of an animal cell?