Answer to Question #337352 in Statistics and Probability for Chris

Question

The paper “Effect of long-term blood pressure control on salt sensitivity” [Journal of

Medicine (1997) 28:147–156] describes a study evaluating salt sensitivity (SENS) after a period of

antihypertensive treatment. Ten hypertensive patients (diastolic blood pressure between 90 and

115 mmHg) were studied after at least 18 months on antihypertensive treatment. SENS readings,

which were obtained before and after the patients were placed on an antihypertensive treatment,

are given here:

Patient 1 2 3 4 5 6 7 8 9 10

Before treatment 22.86 7.74 15.49 9.97 1.44 9.39 11.40 1.86
6.71 6.42

After treatment 6.11
4.02 8.04 3.29
0.77 6.99 10.19 2.09 11.40 10.70

a. Is there significant evidence that the mean SENS value decreased after the patient

received antihypertensive treatment?

b. Estimate the size of the change in the mean SENS value.

c. Do the conditions required for using the t procedures appear to be valid for these

data? Justify your answer

Answer 1

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