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{"ops":[{"insert":"The paper \u201cEffect of long-term blood pressure control on salt sensitivity\u201d [Journal of"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"Medicine (1997) 28:147\u2013156] describes a study evaluating salt sensitivity (SENS) after a period of"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"antihypertensive treatment. Ten hypertensive patients (diastolic blood pressure between 90 and"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"115 mmHg) were studied after at least 18 months on antihypertensive treatment. SENS readings,"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"which were obtained before and after the patients were placed on an antihypertensive treatment,"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"are given here:"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"Patient 1 2 3 4 5 6 7 8 9 10"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"Before treatment 22.86 7.74 15.49 9.97 1.44 9.39 11.40 1.86 \u00016.71 6.42"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"After treatment 6.11 \u00014.02 8.04 3.29 \u00010.77 6.99 10.19 2.09 11.40 10.70"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"a. Is there significant evidence that the mean SENS value decreased after the patient"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"received antihypertensive treatment? "},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"b. Estimate the size of the change in the mean SENS value."},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"c. Do the conditions required for using the t procedures appear to be valid for these"},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":""},{"insert":"\n"},{"insert":"data? Justify your answer"},{"insert":"\n"}]}
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