Biology Answers

Over the last few years, your friend Angela has developed fibrous nodules in many areas of her skin. She recently confided that she has an inherited disorder of the nervous system that causes these bumps. What disease might Angela have? How can a nervous disorder cause a skin lesion?

What change in the climate may have helped more soay sheep to survive winters?

. List and discuss, in your own words, the four key parameters of the Michaelis–Menten Equation. Your response must clearly outline the definition of each of the parameters,and its application to enzyme activity/substrate interaction affinity/catalytic efficiency

What effect does insulin have on glucose in the blood?

you briefly enter in an expert cave and shortly after emerging several hours later you begin to experience difficulty forcing your muscle to reduce the movements required for breathing and it’s hard to make your legs move so that you can walk what happened?

DNA polymerase I (Pol I) of E. coli consists of three functional parts (domains): an N-terminal domain with 5´ to 3´ exonuclease activities required for removal of the RNA primer, a central domain responsible for 3´ to 5´ exonuclease proofreading, and a C-terminal domain with polymerase activity. Pol I is thought to simultaneously remove RNA primers and fill in the gaps that result. A group of proteins known as RNaseH also have 5´ to 3´ exonuclease activity and can thus remove RNA primers. However, they lack the other two functions observed for Pol I. Predict the ability of the following mutants to replicate DNA:(1) a strain with a mutant gene encoding Pol I such that it no longer has polymerase activity (but retains both types of nuclease activities);   (2) a strain without RNaseH proteins; 

You can smell sulfur when boiling eggs. What amino acids do you expect in the egg?

DNA polymerase I (Pol I) of E. coli consists of three functional parts (domains): an N-terminal domain with 5´ to 3´ exonuclease activities required for removal of the RNA primer, a central domain responsible for 3´ to 5´ exonuclease proofreading, and a C-terminal domain with polymerase activity. Pol I is thought to simultaneously remove RNA primers and fill in the gaps that result. A group of proteins known as RNaseH also have 5´ to 3´ exonuclease activity and can thus remove RNA primers. However, they lack the other two functions observed for Pol I. Predict the ability of the following mutants to replicate DNA:

(1) a strain with a mutant gene encoding Pol I such that it no longer has polymerase activity (but retains both types of nuclease activities)

DNA polymerase I (Pol I) of E. coli consists of three functional parts (domains): an N-terminal domain with 5´ to 3´ exonuclease activities required for removal of the RNA primer, a central domain responsible for 3´ to 5´ exonuclease proofreading, and a C-terminal domain with polymerase activity. Pol I is thought to simultaneously remove RNA primers and fill in the gaps that result. A group of proteins known as RNaseH also have 5´ to 3´ exonuclease activity and can thus remove RNA primers. However, they lack the other two functions observed for Pol I. Predict the ability of the following mutants to replicate DNA:

(1) a strain with a mutant gene encoding Pol I such that it no longer has polymerase activity (but retains both types of nuclease activities);   

(2) a strain without RNaseH proteins;