Question #51596
Explain why the Red Blood Cells of an individual are not normally destroyed as a result of innocent bystander lysis by complements?
When complement will cause lysis of an individual's own RBC?
When complement will cause lysis of an individual's own RBC?
Expert's answer
Normally, the surface of RBC contains the markers - protein inhibitors of complement system, such as CD59.
When an individual organism acquires hypersensitivity its antibodies direct against antigens of the own RBC. The resulting Ag-Ab complexes activate complement, leading to cell lysis.
When an individual organism acquires hypersensitivity its antibodies direct against antigens of the own RBC. The resulting Ag-Ab complexes activate complement, leading to cell lysis.
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#339914 on Dec 2023
#339914 on Dec 2023