Several features can be used to distinguish blastula and gastrula a microlecithal, mesolecithal, or macrolecithal organisms:
- microlecithal (sea urchin) - holoblastic cleavage that results in the formation of a pear-shaped blastula with a large spacious blastocelic cavity and a wall consisting of one layer of cells. Blastomers are equal in size and yolk is almost absent.
- mesolecithal (frog) - holoblastic cleavage that results in the formation of a blastula with a small cavity located towards the animal pole and two-layered wall (epiblast and hypoblast). Blastomers are unequal in size and yolk is moderate.
- macrolecithal (chicken) - meroblastic cleavage that is restricted only to around blastodisc. As a result, the blastula is represented by a flat disc located on the yolk. The disc consists of two zones - area pellucida and area opaca.
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