Question

Which of the following buffers act on long term basis to regulate ph of blood: a) haemoglobin buffer b) bicarbonate buffer c)phosphate buffer d) ammonia buffer e) plasma proteins

Answer 1

 

The bicarbonate buffer in the renal system acts on long term basis to regulate the blood ph. The renal response takes 6-12hours with a maximum effect reached between 3-4days. The maximum effect is insufficient to return plasma ph to normal but because of the additional renal contribution the ph is returned towards normal.