Question

what is the structure-activity relationship for sulphonamides. Draw the molecular formula, which
of the groups can be varied and which are essential.
(drug chemistry) please solve it.

Answer 1

Sulphonamides are antimicrobial agents that contain a sulfonamide group. They act as competitive inhibitors of the bacterial enzyme dihydropteroate synthase. This enzyme is involved in the synthesis of folate.