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Major product reaction between butan-1-ol and PBr3 reagents.
What are the applications of retinal. Give detailed answer.
Write elucidation of retinal in detail.
Explain extraction of retinal in detail.
Propose a mechanism for a reaction propanal with1,2-ethanediol, H+ and heat


3.2) Propose a mechanism for an acid catalyzed reaction of benzaldehyde with

NH2OH


3.3) Propose a mechanism for a reaction butanone with PhMgBr then acidic workup.
Synthesize the following molecule from benzene and any other organic/

inorganic reagents

NO2

O
On which ring and at what position(s) of the compounds shown below will

electrophilic aromatic substitution take place? Explain your answer in detail.

(a)

C N

H

H3C

O

(b)

C N

H

O

O2N

CH3

(5)

2.3) The following scheme is proposed for the synthesis of 4-bromobenzoic acid:

NH2 NH2

Br2

i) NaNO2

/HCl

ii) CuCN

Br

CN

Br

CN

Br

H3O

+

Briefly discuss the limitations of the above scheme and then propose a route

that would accomplish the desired product.
2-Butanol+H2SO4
Explain why a methoxy group (CH3O) increases the rate of electrophilic

aromatic substitution, but decreases the rate of nucleophilic aromatic

substitution.

On which ring and at what position(s) of the compounds shown below will

electrophilic aromatic substitution take place? Explain your answer in detail.


C N

H

H3C

O



C N

H

O

O2N

CH3

The following scheme is proposed for the synthesis of 4-bromobenzoic acid:

NH2 NH2

Br2

I) NaNO2

/HCl

ii) CuCN

Br

CN

Br

CN

Br

H3O

+

Briefly discuss the limitations of the above scheme and then propose a route

that would accomplish the desired product.

Synthesize the following molecule from benzene and any other organic/

inorganic reagents

NO2

O


Propose a mechanism for a reaction propanal with1,2-ethanediol, H+ and heat


Propose a mechanism for an acid catalyzed reaction of benzaldehyde with

NH2OH


Propose a mechanism for a reaction butanone with PhMgBr then acidic workup
How does isotopes labeling helps in determining the mechanism of a reaction
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