structure of Na4 [Fe6]
Question 1) - Calculate the total number of conformations generated in a drug molecule with single rotatable bond and 2.4° increment of torsion angle?
Question 2) - Lamivudine is a drug used for the treatment of HIV (AIDS). This drug stop HIV from infecting cells in the body. Only the (-)-enantiomer of lamivudine is registered for the treatment of HIV because it is more active and less toxic than either the (+)-enantiomer or the racemate. In the (-)-enantiomer, the chiral centre at position 2 has the R configuration and the chiral centre at position 5 has the S configuration. Draw the structure of (-)-lamivudine using hashed and wedged line notions that represents R configuration at 2 and S configuration at 5. Need to show your work-up. NH2 N N O O S OH
what is Jones oxidation and write the mechanism of Jones oxidation?
Which of these starting materials could generate this as a major product?
3-methyl-2butanol
while dealing with a compound you found that its nature is acidic and it contains a ketonic group also however it also delocalises water and total no. of carbon atoms was found 7. what is the compound?
A liquid C6H12O2, was hydrolized with water and acid to give an acid A and an alcohol B. Oxidation of B with chromic acid produced A. This formula of the original compound is?
Write an equation for the acid-base equilibrium of aniline and water. Label each species in the equilibrium as either an acid or la base
Consider the reaction MnO2 + 4HCl → MnCl2 + Cl2 + 2H2O. If the both the
reactants have a mass of 100 grams, which of the two will be used up first? How
many grams of MnCl2 will be produced after the reaction? (MnO2 =
86.94 g/mol, HCl = 36.46 g/mol, MnCl2 = 125.8 g/mol)
How would you carry out the following reactions? More than one
step may be required.
• benzene → m-bromoacetophenone
• 1-methylcyclohexene → 2-methylcyclohexanone
How would you use a Grignard reaction on an aldehyde or ketone to
synthesize the following compounds?
• 2-pentanol
• 1-phenylcyclohexanol