Answer to Question #176834 in Organic Chemistry for alaa alsale

Question

Research case studies in order to consider the formation of different isomers during manufacture, how their presence may influence the industrial process, the differences in properties that they might have, and the possible consequences of ignoring the presence of isomerism.

Analyze the therapeutic or chemical effects of isomerism. Research the drugs thalidomide and ibuprofen, and their therapeutic effects.

Compare the structures and properties of the optical isomers in each case study. Explain why one of these drugs is only available as a single optical isomer whilst the other is sold as a racemic mixture (a 50:50 mixture of both optical isomers)

Answer 1

Drug isomerism has opened a new era of drug development. Currently, knowledge of isomerism has helped us in introducing safer and more effective drug alternatives of the newer as well as existing drugs. Many existing drugs have gone chiral switch i.e., switching from racemic mixture to one of its isomers.

If one is optical active then having racemic mixture formed .

One is meso compound so optically inactive .