Answer to Question #141462 in Organic Chemistry for Sofia

Question

If a chemist is going to prepare a chromatography using diethyl ether and ethanol. Which solvent would they use to start the elution? What would happen if they used the other instead?

Answer 1

Solution.

Diethyl ether and ethanol chromatography is a development-displacement chromatography. Diethyl ether is the developer, and ethanol is the displacer. Therefore, to begin with, the column is filled with the test solution, then a developer is added, and then a displacer. If we add a preemptor at the beginning, we won't get completely separated components. In other words, the separation efficiency will be low.

Answer:

Diethyl ether and ethanol chromatography is a development-displacement chromatography. Diethyl ether is the developer, and ethanol is the displacer. Therefore, to begin with, the column is filled with the test solution, then a developer is added, and then a displacer. If we add a preemptor at the beginning, we won't get completely separated components. In other words, the separation efficiency will be low.