Question

Diosmetin is a natural flavonoid present in the rind of ‘kalamansi’ and the leaves of ‘alagao’. It is a good antioxidant and anti-inflammatory agent. It is medically prescribed to treat hemorrhoids and varicose veins. Its molecular weight is 300.26 g/mol.

(a) How many millimoles (mmol) of diosmetin are in a caplet that contains 250 mg of diosmetin?

(b) If one is prescribed to take 3 caplets a day, how many milligrams of diosmetin are to be taken a day?

(c) If one has to obtain 1.5 mole of diosmetin for treatment, how many caplets does he need?

Answer 1

Molar mass of diosmetin $= 300.26\ g/mol$

$(a)$ Millimoles in $250 \ mg$ of diosmetin or one caplet$= \frac{250 \times 10^{-3}}{300.26}\times 10^3 =$ $0.832$

$(b)$ One caplet contain $250$ $\ mg$ of diosmetin.

Three tablets would contain $250\times 3= 750\ mg$ of diosmetin.

$(c)$ Required amount $=$ 1  mole $= 1000$ millimoles.

Millimoles in 1 \caplet$= 0.832$

Number of caplets required for this amount$=\frac{1000}{0.832}=$ $1201.92\approx 1202$