Discuss 2,3 BPG pathway in erythrocyte and its significance.
2,3-DPG levels in the erythrocytes help regulate hemoglobin oxygenation (Figure 26.6). Unloading of oxygen at the P O 2 in tissue capillaries is increased by 2,3-DPG, and small changes in its concentration can have significant effects on oxygen release. ... Note that 2,3-DPG decreases the affinity of hemoglobin for oxygen.
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