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■Assess what happens in the following error mutations and show how this affects the proteins produced

Missense, nonsense, silent, insertion, deletion, duplication, frameshift

Include examples to demonstrate points

a farmer grows crops in one of his fields. suggest how he could estimate the chemical energy store in the dry mass of one of his cabbage


Phenylketonuria, a Metabolic disease in humans, is caused by a recessive allele, k. If two heterozygous carriers of the allele marry and plan a family of five children:

a. What is the chance that all their children will be normal?

b. What is the chance that four children will be normal an done affected?

c. What is the chance that at least three children will be normal?

d. What is th echance that the first child will be a normal girl?


What is the root exit zone according to Microvascular decompression. Can you describe it?


Discuss the rumen as an example of a complex ecosystem

a. In mice, the allele for coloured fur (C ) is dominant over white fur (c). The allele V for normal behaviour is dominant over the allele v for abnormal behaviour.



Give the genotypes of the parents in each of the following crosses:



i. Coloured, normal mice mated with white, normal mice produced 29 coloured, [5] normal and 10 coloured, abnormal progeny




ii. Coloured, normal mice mated with coloured, normal mice produced 35 coloured, normal, 13 coloured, abnormal, 11 white, normal and 4 white, abnormal progeny




The velocity of an enzyme-catalyzed reaction that follows Michaelis-Menten kinetics was


measured at several substrate concentrations (shown below).


i. Calculate 𝐾M and V𝑚𝑎𝑥 from the data given.


ii. Determine KM and Vmax


iii. The second set of velocities represent the rate of the reaction when an inhibitor is


added. Plot these on the same graph as the first and determine KM and Vmax


iv. What type of inhibitor is it?


[S](M) V0 (μM/min) V(+ inhibitor)


0.00006 6.66 4


0.0001. 9.30 3


0.002. 15 6


0.006 22.03 8


0.08 29 9


0.2. 35.6 10.6

With help of diagram explain the pentose phosphate pathway or hexose monophosphate shunt,



Mycotickeretis, diagnosis, history, control and treatment

To what extent is biotic invasion and native species loss creating ecosystems with altered properties?

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