Answer to Question #185614 in Zoology for Raffy Georpe

Question

How stable is life's genetic code? How are instances of stability and instability explained?

Answer 1

Basically, genetic code is mainly understood to be efficient in limiting the effects of errors of mistranslation. Notably, in the case of a misread codon the protein function and structure remain unaltered especially in codes with similar biochemical properties.

Majorly, previous studies have made efforts to address the question of stability and instability. In this case, there have been estimations of randomly generated codes which basically do better than the genetic codein respect of overall robustness. By use of a simplified evolutionary motivated two-letter version of genetic code, the general principles of the most stable coding are discussed. In this aspect, complete enumeration is reduced code proves maximum stability in regard to point mutations and shifts in the reading frame that requires fixation of the middle letters within codons especially in groups with different psycho-chemical properties thus explaining a major key aspect of the universal genetic code.