Answer to Question #256149 in Biology for Richard

Question

example of nonsense mutation

Answer 1

A nonsense mutation is a genetic mutation in a DNA sequence that results in a shorter, unfinished protein product. Thus, nonsense mutations occur when a premature nonsense or stop codon is introduced in the DNA sequence.

Examples of diseases in which nonsense mutations are known to be among the causes include: Cystic fibrosis (caused by the G542X mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) Beta thalassaemia (β-globin) Hurler syndrome.