Question

Instructions for making proteins found in the nucleus

Answer 1

In the cell, proteins that are located in the nucleus are synthesized on free cytoplasmic ribosomes. The nuclear proteins contain specific amino acid sequence - nuclear localization signals that are recognized by nuclear transporters - importins, that interact with nuclear localization signals, as well as components of the nuclear pore. As a result, importins direct proteins containing nuclear localization signal into the cell nucleus.