Answer to Question #165827 in Molecular Biology for Emma

Question #165827

 you could describe the mechanism of drugs such as the statins, which inhibit the function of the enzyme HMG-CoA reductase and so reduce the synthesis of cholesterol in the body. You could report the manner in which the inhibitors interact with their enzyme target, if they are allosteric or competitive and what the result of that inhibition is to the cell. (Try to pick an alternative example to statins).


1
Expert's answer
2021-02-23T08:07:48-0500

The allosteric inhibitor binds to an enzyme at a site other than the active site. The shape of the active site is altered so that the enzyme can no longer bind to its substrate.

The competitive inhibitor resembles the substrate and binds to the active site of the enzyme. The substrate is thereby prevented from binding to the same active site. A competitive inhibitor diminishes the rate of catalysis by reducing the proportion of enzyme molecules bound to a substrate.


Need a fast expert's response?

Submit order

and get a quick answer at the best price

for any assignment or question with DETAILED EXPLANATIONS!

Comments

No comments. Be the first!

Leave a comment

LATEST TUTORIALS
New on Blog
APPROVED BY CLIENTS