Answer to Question #301603 in Human Anatomy and Physiology for Noah

Question

 These two questions about anesthetizing a rabbit

1.How does the coagulation time of the test tube with heparin change? Why?

2. How does the coagulation time of the test tube with Lung tissue immersion liquid change?

Answer 1

Once active thrombosis has developed, larger amounts of heparin can inhibit further coagulation by inactivating thrombin and preventing the conversion of fibrinogen to fibrin. Heparin also prevents the formation of a stable fibrin clot by inhibiting the activation of the fibrin stabilizing factor.