Genetics Answers

In humans there is a disease called Phenylketonuria (PKU) which is caused by a recessive allele. People with this allele have a defective enzyme and cannot break down the amino acid phenylalanine. This disease can result in mental disability or death. Let "E" represent the normal enzyme. Also in humans is a condition called galactose intolerance or galactosemia, which is also caused by a recessive allele. Let "G" represent the normal allele for galactose digestion. In both diseases, normal dominates over recessive. If two adults were heterozygous for both traits (EeGg), what are the chances of having a child that is completely normal? Has just PKU? Has just galactosemia? Has both diseases?

Explain the principal of recombinant DNA technology and list applications of genetic engineering technique.

How would differences in gene methylation cause a difference in phenotype between two people with identical genes?

Differentiate between monozygotic and dizygotic twins. What is the use of twin studied? State Hellin's Law and discuss it's applications in twin studied.

using punnet square, summarize the expected results, both genotypically and phenotypically, of the following crosses. R-round r-wrinkled.
a) RR x rr
b) Rr x Rr
c) Rr x rr

one type of pet mouse occurs in either grey or white coats. A client would like to produce a purebreeding strain of grey coloured mice. he has tried mating grey mice only with other grey mice, but in many cases the litters include some white mice.
explain the theory and the steps that your client must take to determine which of his grey mice will breed true

I have a strain of MG1655 E.coli. It has a Cm cassette inserted into my locus of interest via lambda red approach. How can this strain be used to generate a PCR fragment with a high chance of recombination with a CFT073 strain genome?

Calculate the degrees of freedom if 5 defined classes are being rested. Show your work.

Describe origin and phenotypic effect of the following structural chromosomal aberrations deletion, duplication, inversion, translocation.

Explain why each parent has two of each chromosome. How do the chromosomes compare?