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Explain the concept of ‘multiple alleles’. Use the ABO blood grouping system to illustrate your answer. Produce a table to illustrate all possible phenotypes and their respective genotypes
Outline Mendel's first law.
Briefly explain the terms,
• monohybrid inheritance
• dominant and recessive
• genotype and phenotype
• homozygous and heterozygous
Use specific examples with genetic notation to illustrate your answer and show links between the terms
(A) Mendel’s 1st law - state
(b) Accurate definition of each term and link between them
(c) Illustration and explanation of test cross.
(d) Explanation of multiple alleles and table
About the history of DNA (The Race for the Double Helix)
How many controlled experiments did Watson and Crick carry out themselves and used to support their findings concerning the structural arrangement of DNA?
Using a worked example show how would you determine if a tall plant was
heterozygous or homozygous tall. Illustrate your answer with appropriate
crosses.
(d) Explain the concept of ‘multiple alleles’. Use the ABO blood grouping system to illustrate your answer. Produce a table to illustrate all possible phenotypes and their respective genotypes.
(It is not sufficient to copy and paste a table from a website)
From the sequence of RNA -C, U, A, C, A- what would you expect the complement strand of DNA to be?
In certain rose plants, white roses and red roses are incompletely dominant to one another. When a red rose is crossed with a white rose, a pink rose will result. What is the probability of producing more pink roses from two pink parents?
Achondroplasia, a form of Hereditary Dwarfism ( 10 points)
Achondroplasia is a hereditary constitutional bone disorder; it is the most common type of dwarfism, in which the child’s arms and legs are short in proportion to body length and have a characteristic face . This disease is caused by a mutation of the fibroblast growth factor receptor-3 gene (FGFR3) on human chromosome 4.
Document 1 : A pedigree of a family whose certain members are affected by Achondroplasia.
1- Indicate if the allele responsible for the disease is dominant or recessive. Justify the answer.
2- Determine the chromosomal localization of the gene responsible for Achondroplasia .
3- Specify the genotype of each of the individuals (I-1), (III-9), and (IV- 4).
Homozygous fetuses that possess two copies of the mutant gene are not viable, and pregnancy is naturally interrupted.
4- Determine the risk for the couple III- 9 and III- 10 to have a third child affected by Achondroplasia.
In dragons, black body color is dominant to green body color. Cross one homozygous dominant dragon with one homozygous recessive dragon.
What are the genotypes of the parents
Using mainly labelled diagrams, (and some explanation) describe the sequence of events in the process of Meiosis in eukaryotic cells.
Indicate clearly where the opportunities arise in meiosis for genetic variation and outline and illustrate briefly how this happens
Explain the terms Chromosome, Chromatid, Gene, Allele.
(Use genetic notation (symbols for alleles) and annotated diagrams to illustrate your response. Show links between the terms)
2. Using mainly labelled diagrams, (and some explanation) describe the sequence of events in the process of Meiosis in eukaryotic cells.
Indicate clearly where the opportunities arise in meiosis for genetic variation and outline and illustrate briefly how this happens.
