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The presence of horns in cattle is controlled by a single gene. The hornless (H) condition is dominant over the horned (h) condition. A hornless cow was crossed repeatedly with the same horned bull. The following results were obtained with the F1 offspring: 8 hornless, 7 horned. What are the parents’ genotypes? 


  1. In rabbits, spotted fur is dominant over solid-coloured fur. A solid-coloured rabbit is mated to a homozygous spotted rabbit
  2. What is the genotype of the offspring?
  3. What is the phenotype of the offspring?
  4. If two of the offspring are crossed, what would be the genotype and phenotype of the F2 generation?




Indicate clearly where the opportunities arise in meiosis for genetic variation and outline and illustrate briefly how this happens.


So by using CRISPR, which step in gene expression would you want to target and why?


Explain the terms Chromosome, Chromatid, Gene, Allele.

(Use genetic notation (symbols for alleles) and annotated diagrams to illustrate your response. Show links between the terms)


Given a cross between 2 plants. The male is pure with long stem and the female is pure with short stem. All F1 generation has long stems. a) Determine the dominant and the recessive alleles. b) Do the necessary factorial analysis to find the genotypic and phenotypic percentages of F1 and F2 generations


Explain the concept of ‘multiple alleles’. Use the ABO blood grouping system to illustrate your answer. Produce a table to illustrate all possible phenotypes and their respective genotypes


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Outline Mendel's first law.

Briefly explain the terms,

• monohybrid inheritance

• dominant and recessive

• genotype and phenotype

• homozygous and heterozygous

Use specific examples with genetic notation to illustrate your answer and show links between the terms


(A) Mendel’s 1st law - state

(b) Accurate definition of each term and link between them

(c) Illustration and explanation of test cross.

(d) Explanation of multiple alleles and table



About the history of DNA (The Race for the Double Helix)


How many controlled experiments did Watson and Crick carry out themselves and used to support their findings concerning the structural arrangement of DNA?



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