Genetics Answers

Phenylketonuria, a Metabolic disease in humans, is caused by a recessive allele, k. If two heterozygous carriers of the allele marry and plan a family of five children:

a. What is the chance that all their children will be normal?

b. What is the chance that four children will be normal an done affected?

c. What is the chance that at least three children will be normal?

d. What is th echance that the first child will be a normal girl?

a. In mice, the allele for coloured fur (C ) is dominant over white fur (c). The allele V for normal behaviour is dominant over the allele v for abnormal behaviour.

Give the genotypes of the parents in each of the following crosses:

i. Coloured, normal mice mated with white, normal mice produced 29 coloured, [5] normal and 10 coloured, abnormal progeny

ii. Coloured, normal mice mated with coloured, normal mice produced 35 coloured, normal, 13 coloured, abnormal, 11 white, normal and 4 white, abnormal progeny

In the X-Y and Z-W systems of sex determination, which sex is the heterogametic sex, the male or female?

In the X-Y and Z-W system of sex determination, which sex is the heterogametic sex, the male of female

Write the sequence of peptide that would be released from the following peptide by the treatment of trypsin? Heptadecapeptide Cortistatin

DRMPCRNFFWKTFSSCK

Fill in punnett square below by applying the mendelian inheritance of pattern

Percent probability of male offspring :

Percent probability of femalu offspring :

Please explain why mendel rejected the blending inheritance theory?

Please define Mendel's principles of inheritances?

You are interested to study the mutation in the regulatory gene (lach) of a lac operon which significantly alters the shape of repressor protein produced, causing loss of function. By using separate labelled diagrams, describe briefly the actions of the normal and mutated fac operon in absence of lactose.

As a laboratory researcher, you have obtained three (3) human gene sequences from the gene bank. Of which. they were found out to be template that encoded for peptide hormone A, hormone B and hormone C in human body. The production of these hormones can have pharmaceutical uses in the future, for example, hormone replacement therapy in treating disease. Expression of biological information is one of the important steps to produce exogenous protein in biotechnology field. To figure this out, you look into the process of protein synthesis that occurs naturally in a cell.

Gene sequence for hormone A:

3' ...TAC TGG ATG CGC CTC CTG CCC CTG GCG CCA ATT ... 5¹

Gene sequence for hormone B:

3'...TAC GTT ATG CCC ATA TAG TTT CCT GAG AAG ATC... 5'

Gene sequence for hormone C:

3' ...TAC TCC TTG CGG CTC GTA TCT CTG TCG CAA ACT... 5¹