Chromosome condensation is caused by the condensin complex, among other proteins, and is necessary to prevent chromosomes from being entangled during chromosome segregation. Nucleosomes, the repeating building blocks of chromatin, vary in the composition of their histone protein components. This is due to the fact of incorporation of different variations of histones and their posttranslationsl modifications. So yes different llevels of condensation of chromsomes require different histones and their number increases during condensation.
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