Answer to Question #81877 in Genetics for susan Guido

Question #81877

Recombinase is a protein that finds adjacent pieces of DNA that have nearly identical DNA sequences, facilitates a backbone break in each piece of DNA near the identical sequence, physically rearranges the pieces of DNA, and then facilitates backbone repair. How does recombinase know when it’s found the right combination of DNA?

Expert's answer

Recombinase does not know if the produced combination is correct. It is just due to chance that the correct sequence is restored.