Answer to Question #56196 in Genetics for Astha Agarwal

Question

What is difference between VNTR and probe?Write at least 5

Answer 1

1. Type of nucleic acid: DNA (VNTR); either DNA or RNA (probe).
2. Sequence type: always tandem repeats, depends on sequence of template chain (VNTR); depends on target sequence (probe).
3. Sequence polymorphism: hypervariable (unique for each individual in case of VNTR); less variable (based on typical consensus sequence in case of probe).
4. Origin: part of DNA synthesized in vivo during transcription and isolated from cells (VNTR), sequence synthesized in vitro (probe).
5. Role in genetic analysis: target sequence which is being detected (VNTR); marker used for detection (probe).