Answer to Question #294666 in Genetics for Rookie

Question

Explain why the Mendelian inheritance does not apply to the inheritance of alleles in individuals with Tay Sachs disease

Answer 1

Explain why the Mendelian inheritance does not apply to the inheritance of alleles in individuals with Tay-Sachs disease

Tay-Sachs disease is a genetic condition affecting the nervous system. The condition is an autosomal recessive pattern. The offspring inherits one mutation from each parent, and both copies of the inherited genes have variants. Therefore, Tay-Sachs disease is not inherited following the Mendelian inheritance since it involves the inheritance of gene alleles with incomplete dominance. In incomplete dominance, neither of the inherited alleles is utterly dominant over the other. Unlike in, Mendelian inheritance, where one allele is dominant over the other.