Question #261146
Write the sequence of peptide that would be released from the following peptide by the treatment of trypsin? Heptadecapeptide Cortistatin
DRMPCRNFFWKTFSSCK
Expert's answer
Trypsin is a serine protease. It cleaves proteins into peptides with an average size of 700-1500 daltons. It is highly specific, cutting at the carboxyl side of arginine and lysine residues. The C-terminal arginine and lysine peptides are charged, making them detectable by Mass Spectrometry.
