Answer to Question #212885 in Genetics for Zithin

Question

According to Swedish geneticists, some forms of schizophrenia are inherited as autosomal dominant characters. In homozygous potency, the gene is 100%, and in heterozygotes it is 20%. Determine the probability of giving birth to sick children in a family where both parents are heterozygous. What does penetrance show?

Answer 1

The familial nature of schizophrenia does not conform to simple dominant or recessive modes of inheritance. Schizophrenia is a common and severe mental illness of thought, emotion, and behavior that affects about 1% of the general population.