Answer to Question #163881 in Genetics for Lara

Question

Anodontia is a recessive hereditary disease which causes the absence of teeth or any tooth germ.

First cross: The father has a normal phenotype and the mother has the disease, the sons are all affected and the girls are always healthy.

Second cross: The father is affected and the mother is healthy, sons and daughters can have a normal or sick phenotype.

1. Determine the chromosomal location of the gene responsible for this disease. Then perform a factorial analysis to verify the above results

Answer 1

It is associated with the group of skin and nerve syndromes called the ectodermal dysplasias. Anodontia is usually part of a syndrome and seldom occurs as an isolated entity.