Co-adaptation is a process observed when two species adapt to a certain factor while the adaptations of each species depend on another species. As a result, the adaptation of the species occurs when they are in a pair. Co-adaptions can be observed among species, as well as genes, proteins, etc. Co-evolution is a long term co-adaptation. Co-adaptation is evidence of co-evolution. Co-evolution is observed when co-adaptations of two species or two genes occur during the evolutionary processes accompanied by the significant modification of species or genes and even formation of new species and new genes.