Question

Explain the role of the Endoplasmic Reticulum in protein folding. Consider quality control, the solutions to folding and refolding, and the degradation of proteins.

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Answer 1

The ER has a central role in lipid and protein biosynthesis. Its membrane is the site of production of all the transmembrane proteins and lipids for most of the cell's organelles, including the ER itself, the Golgi apparatus, lysosomes, endosomes, secretory vesicles, and the plasma membrane.