Biochemistry Answers

What structural characteristics are common to all the amino acids that are found in
mammalian proteins and draw the structure of the tripeptide Pro-Asp-Lys in the ionic
form that predominates at pH 7. Show all atoms (including hydrogens) as well as
any charges as necessary.

What does pH measure?


the total number of base molecules in solution

the concentration of hydrogen ions in solution

the total number of acid molecules in solution

the concentration of oxygen atoms in soluti

1) Acetyltransferase enzymes modify a lysine side chain with an acetyl group. Titration of the pKa of the lysine substrate reveals the pKa value to be 8.1. What is the likely environment surrounding the lysine sidechain before it is acetylated? (Choose all that apply)

Cannot hypothesize based on the given information and prior knowledge
Water accessible active site in the enzyme
Water inaccessible highly polar active site
Largely non-polar and water inaccessible active site
Solvent exposed and near the enzyme surface

Explain, with the use of a graph, why ATP is able to perform useful work in a cell?

Show how ΔG is related to membrane potential and ion concentration

The reaction catalyzed by malate dehydrogenase has a ΔGo/ of +29kJmol-1.

Can this reaction proceed spontaneously? Explain your answer.

What does the second law of thermodynamics state? If the entropy of a folded protein is lower than that of the protein in its denatured state explain how the folding process be spontaneous?

What is classical thermodynamics and how exactly can it be applied to open systems like in biology?

Discuss the functions of pepsin, trypsin and chymotrypsin.

Describe the functions two three soluble vitamins and diseases that arise as
a result of their deficiency.