Biochemistry Answers

What are: the Common Models of Absorption across Membranes and Transport to Target Sites and the Major Modes/Pathways for Biotransformation and Elimination and for the chemical for the following chemicals with giving one example of a Mechanism of Toxicity at the Major Target Site:
1- Lead (inorganic)
2- Toluene
3- Methyl ethyl ketone (MEK)

Please answer the whole question. Thank you. Haley

What are the Major Modes/Pathways for Biotransformation and Elimination for the chemical MEK?

What are the Common Models of Absorption across Membranes and Transport to Target Sites for the chemical MEK?

How
many
tritium
atoms
(3H)
are
incorporated
into
palmitate
when
fatty
acid
synthesis
is
carried
out
in
vitro
with
the
following
labeled
substrate?
Explain
your
answer

Mammals cannot undergo net synthesis of carbohydrate from acetyl-CoA, but the
carbons of acetyl-CoA can be incorporated into glucose and amino acids. Present pathways by which
this could come about

What is the metabolic significance of the following observations? (1) Only the liver form of
pyruvate kinase is inhibited by alanine, and (2) only gluconeogenic tissues contain appreciable levels of
glucose-6-phosphatase?

Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than
pyruvate carboxylase, to be the primary target for regulation of gluconeogenesis at the level of control
of enzyme synthesis?

(6 points) Write a one or two-sentence response to the following questions/statements.
(a) In liver, glucagon stimulates glycogen breakdown via cAMP dependent signaling. Although one
might expect glucagon also to stimulate catabolism of the glucose formed (much like epinephrine
stimulates catabolism of glucose in muscle), glucagon inhibits glycolysis and stimulates
gluconeogenesis.
(b) An individual with glucose-6-phosphatase deficiency suffers from chronic hypoglycemia.
(c) 14CO2 was bubbled through a suspension of liver cells that was undergoing gluconeogenesis from
lactate to glucose. Which carbons in the glucose molecule would become radioactive

what is the function of a cell membrane?

what phase is the period during the life of a cell between the end of mitosis and the synthesis of more genetic material.