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Based on the coverage of the regulation of glycogen metabolism, describe or predict what effect the following real or hypothetical mutations might have on an infant born with the described genetic defects. Describe the effects both at the level of glycogen structure and/or metabolism and potential symptoms: A) Mutation in muscle glycogen phosphorylase that weakens binding of AMP. B) Mutation in liver glycogen phosphorylase that inhibits binding of glucose. C) Mutations that inhibit the activity of debranching enzyme.
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