Which of the following promotes wakefulness?
A-Histamine
B-Leptin
C-Ghrelin
D-Melatonin
None of the above substances can cause or promote wakefulness. All the substances named above except Melatonin are not even related to sleep. Melatonin is the hormone that causes us to sleep. So the correct answer is Melatonin because at lower levels it will cause you to wake up
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