Consider expansion of (x+y)n:
(x+y)n=i=0∑n(in)xiyn−i
We need to find coefficient at term x3y3.
We see that all terms of the expansion are in form xkyn−k. So if n=6 coefficient at x3y3 equals to 0.
If n=6 the coefficient at x3y3 equals to
(36)=3!6⋅5⋅4=20