The second factor that becomes important in reactions of substituted benzenes concerns the site at which electrophilic substitution occurs. Since a mono-substituted benzene ring has two equivalent ortho-sites, two equivalent meta-sites and a unique para-site, three possible constitutional isomers may be formed in such a substitution.These reactions involve various steps including hydrogenation and carbon-heteroatom bond cleavage, in which both hydrogen and hydrogen sulfide can play a role. To identify the mechanisms of these reactions, the process of adsorption (and of activation) of H2 and of H 2 S must be well understood.
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