The chemical X has an LD5o of 80 mg/kg. The lethal dose is expressed as the milligrams of X (80 mg) per kilogram of body weight of the test animal (typically rats ). This dose tell s us that 50% of the rats will die if they are given 80 mg of X per kg body weight of the subject animal. Thus, for a person who weighs 100 kg there is a 50% chance that a dose of (80 mg) x (70 kg) = 5600 mg or 5.6 g may be fatal. What is the volume of X (in microlitres) for the fatal dose (LDso) of X that will kill a person who weighs 70 kg? (Density of X = 1.446 g/mL).
Density = mass / Volume .
1.446 g / ml = mass in g / Volume in ml .
Volume in ml. = mass in g / 1.446
Volume in ml = ( 5.6 / 1.446 ) ml .
Volume = 3.8727 ml .
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