Answer to Question #282388 in Physical Chemistry for Nur

Question

What are the applications of molecular emission spectroscopy?

1. Fluorescent active drugs
2. Fluorescent active impurities
3. Drug protein binding

a. I and III

b. Only I

c. Only II

d. I, II and III

e. I and II

Answer 1

Molecular Emission Spectroscopy is a spectroscopic technique which examines the wavelengths of photons emitted by molecules during their transition from an excited state to a lower energy state. 

The emission spectra of molecules can be used in chemical analysis of substances.

• Determination of fluorescent drugs in low-dose formulations in the presence of non-fluorescent excipients.

• In carrying out limit tests where the impurity is fluorescent or can be simply rendered fluorescent.

• Useful for studying the binding of drugs to components in complex formulations

• Widely used in bioanalysis for measuring small amounts of drug and for studying drug-protein binding.

Correct option is d