Question

A chemistry student seeks advise of his Professor before performing the below reaction. However, the Professor does not approve it. He neither quotes that the high temperature (100 C) or long duration (40 h) as an issue. He simply mentions "difficult to handle" reaction. Could you briefly explain the Professor's concern? *

Answer 1

It is reaction should be connection with natural biological compound(e.p:peptid). And Natural compounds not stable for high temperature.