Question #95020

Acid-catalyzed cascade reactions are employed by nature and also by synthetic chemists in the construction of complex polycyclic molecules, including steroids. Provide a mechanism for the following multiple cyclization.


Expert's answer

A cascade reaction is a chemical process that comprises at least two consecutive reactions such that each subsequent reaction occurs only in virtue of the chemical functionality formed in the previous step.

In this reactions, isolation of intermediates is not required.

For a complete answer to the question, it is necessary to know the initial and final product of the synthesis!


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