Answer to Question #93028 in Organic Chemistry for Tanmay

Question

(1)The higher is the oxidation number of the metalion the higher would be efficiency of metal salt as a catalyst ?
(2) in the context of catalyst of n mathylol compounds, any hydroxy substituted organic acid Would give synergistic effect with metal salt.. ?
(3) if 1% add on of crosslinking agent is required the concentration (g/L) of the crosslinking agent in pad liquor at 100% wet expression is 1.... ?

Answer 1

(1) For mononuclear Co and Cu, simple oxidation into the purely higher-valent metal oxidation states are not allowed so that the metal-ligand hybrid orbitalsbecome the targets which should be used not only to store the oxidizing equivalents but also to give substantial impact on the electron density at the oxygen bound to the active metal center. 

(2) Pleasingly, the synergetic catalyst combination of (R)-TRIP and Cp*Ir(III)-diamine·(R)-TRIP (134) was effective in promoting the reductive amination of aromatic methyl ketones 131 and anilines with molecular hydrogen to yield stereogenic amines 132 in excellent yields and selectivities

(3) 10 g/L.