Question

Alkyl halides order of reactivity of sn2 reaction is CH3>p-RX>Sec-RX>tert-RX discuss the factor which are mainly responsible for this order

Answer 1

Answer on question #74611

reactivity of sn2 reaction is CH3>p-RX>Sec-RX>tert-RX

This is due to steric hindrance because SN2 reaction is back side attack of nucleophile .steric hindrance order of alkyl group is tert>sec>primary>CH3

Steric effects in the substrate – the more substituted the carbon center is, the lower the rate of substitution. Reason:

The transition state is the most crowded species on the entire pathway from reactants to products. Therefore steric congestion

will have a pronounced effect on the energy of the Transition state. For tertiary substrates its energy is considerably higher.

Answer provided by AssignmentExpert.com