Answer to Question #61060 in Organic Chemistry for Amit Sharma

Question

a) Explain the following with suitable examples.
i) Aldehyde without  - hydrogen does not undergo Cannizzaro reaction.
ii) Aldehyde must contain  - hydrogen for aldol condensation.
iii) For Michael addition electron withdrawing group must be present with carbon – carbon double bond.
iv) Electron withdrawing substituents at carbonyl carbon increases its reactivity towards nucleophilic addition reactions.
v) Reaction of primary amine, in presence of an acid, with carbonyl compound given an imine. The rate of reaction increases by an increase in acidity but beyond a certain limit, the rate decreases with further increase of acidity.