Question

Suggest the most suitable synthetic routes for preparing 1-phenyl-1-butanol, using benzene and butane only, please mention the reagents required to do so as well. Thank you!

Answer 1

First of all from butane you may produce the corresponding aldehyde
С₄Н₁₀ + О₂ (450 °C, 1—2 МPа, AlPO₄) → С₄Н₈О + Н₂O;
then synthesize benzene halogenide
C₆H₆ + Cl₂ = C₆H₅Cl + HCl
The following reactions will be the reaction of the Grignard
C₆H₅Cl + Mg = C₆H₅ClMg
C₆H₅ClMg + С₄Н₈О (H₂O) = C₆H₅(OH)С₄Н₈