C. Amide Hydrolysis
1. Using structural formulas, write a balanced equation for the reaction of acetamide
with aqueous HCl. Indicate which of the products might be a volatile acid or
volatile base.
2. Using structural formulas, draw a balanced equation for the reaction of
acetamide with aqueous NaOH. Indicate which of the products might be a
volatile acid or volatile base.
3. Red litmus paper turns blue when exposed to a base, but remains red when exposed to an acid. Use the answers to questions 1 and 2 to explain whether you think the litmus paper will change from red to blue if placed above a reaction
where it is exposed to the volatile products of the reaction.
a. Reaction with aqueous HCl:
b. Reaction with aquous NaOH:
"H_\n3\nC\n\u2212\nC\nO_\n2\nN\nH_\n2\n(\na\nq\n)\n+\nN\na\nO\nH\n(\na\nq\n)\n\u2192\nH_\n3\nC\n\u2212\nC\nO\n\u2212\n2\nN\na\n+\n+\nN\nH_\n3\n(\na\nq\n)"
a) Reaction with aqueous HCl: red litmus paper remains red
b) Reaction with aquous NaOH: Red litmus paper turns blue
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